PubMedQA: A Dataset for Biomedical Research Question Answering
Written for the Research library (claude-opus-5-5) from the paper text. Original — aclanthology.org/D19-1259.pdf
Summary
Biomedical QA resources have been either small and expert-labeled (BioASQ has under 3k training items) or large but built automatically, with mostly factoid questions that need little reasoning. The authors use a common pattern in PubMed: many articles have a question as their title and a structured abstract whose conclusion answers it. From these articles they build PubMedQA. A system reads the abstract with its conclusion removed and must answer yes, no or maybe. The removed conclusion serves as a "long answer" that can provide extra supervision. The resource has three parts: 1k items labeled by two M.D. candidates, 61.2k unlabeled items, and 211.3k artificial items made by turning declarative titles into questions with heuristic labels. As a baseline, the authors fine-tune BioBERT in several phases: first on the artificial data, then on pseudo-labeled unlabeled data, then on the labeled set. They also add an auxiliary objective that predicts bag-of-words statistics of the conclusion. The best system reaches 68.1% accuracy, compared with 78.0% for a single human and 55.2% for the majority class. The benchmark tests reasoning over quantitative findings, and it is still far from solved.
Key points
- Subsets: PQA-L has 1k expert-labeled items (55.2% yes, 33.8% no, 11.0% maybe), split into 500 for 10-fold cross-validation and 500 for testing. PQA-U has 61.2k unlabeled items. PQA-A has 211.3k auto-labeled items (92.8% yes, 7.2% no).
- Source: About 760k PubMed articles have question titles, and about 120k of those have structured abstracts. More than half of such titles can be answered with yes/no/maybe, compared with about 1% in Natural Questions and 6% in HotpotQA.
- PQA-A construction: Statement titles with an NP-(VBP/VBZ) structure (found with Stanford CoreNLP) are rewritten as questions and labeled by whether they contain a negation. For PQA-U, a rule-based filter that picks out yes/no/maybe questions agrees with an expert annotator over 93% of the time.
- Results (reasoning-required setting): Multi-phase BioBERT with long-answer supervision gets 68.1% accuracy. A single human gets 78.0%, and the majority baseline gets 55.2%. Other baselines include shallow features, BiLSTM and ESIM with BioELMo.
- Open problems: About 21% of contexts give numbers without any text describing them. The authors suggest generating the long answer as a richer auxiliary task. The data is available at pubmedqa.github.io.
Cited by
- Fast-DetectGPT: Efficient Zero-Shot Detection of Machine-Generated Text via Conditional Probability Curvature
- MEDITRON-70B: Scaling Medical Pretraining for Large Language Models
- M3-Embedding: Multi-Linguality, Multi-Functionality, Multi-Granularity Text Embeddings Through Self-Knowledge Distillation
- A Dataset of Information-Seeking Questions and Answers Anchored in Research Papers
- English Machine Reading Comprehension Datasets: A Survey
- Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing
- Evaluating Large Language Models: A Comprehensive Survey
- Knowledge Unlearning for Mitigating Privacy Risks in Language Models
- BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains
- DataComp-LM: In search of the next generation of training sets for language models
- RA-DIT: Retrieval-Augmented Dual Instruction Tuning
- The Flan Collection: Designing Data and Methods for Effective Instruction Tuning
- DetectGPT: Zero-Shot Machine-Generated Text Detection using Probability Curvature
- Generative Representational Instruction Tuning
- Capabilities of GPT-4 on Medical Challenge Problems
- Can AI-Generated Text be Reliably Detected?
- Fact or Fiction: Verifying Scientific Claims
- RedPajama: an Open Dataset for Training Large Language Models
- Benchmarking Retrieval-Augmented Generation for Medicine
- LinkBERT: Pretraining Language Models with Document Links
- A Survey of Large Language Models
Cite
@inproceedings{jin2019pubmedqa,
title = {{PubMedQA: A Dataset for Biomedical Research Question Answering}},
author = {Jin, Qiao and Dhingra, Bhuwan and Liu, Zhengping and Cohen, William and Lu, Xinghua},
booktitle = {Proceedings of the 2019 Conference on Empirical Methods in Natural Language Processing and the 9th International Joint Conference on Natural Language Processing (EMNLP-IJCNLP)},
year = {2019},
doi = {10.18653/v1/d19-1259},
url = {https://doi.org/10.18653/v1/d19-1259}
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