Science 2022: all accepted papers
- Copper induces cell death by targeting lipoylated TCA cycle proteins ↗Peter Tsvetkov, Shannon Coy, Boryana Petrova et al.4,849 citations
- The complete sequence of a human genome ↗Sergey Nurk, Sergey Koren, Arang Rhie et al.3,060 citations
- Per- and polyfluoroalkyl substances in the environment ↗Marina G. Evich, Mary J. B. Davis, James P. McCord et al.2,106 citations
- Robust deep learning–based protein sequence design using ProteinMPNN ↗Justas Dauparas, Ivan V. Anishchenko, Nathaniel R. Bennett et al.2,051 citations
- Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis ↗Kjetil Bjørnevik, Marianna Cortese, Brian C. Healy et al.2,027 citations
- Exceeding 1.5°C global warming could trigger multiple climate tipping points ↗David I. Armstrong McKay, Arie Staal, Jesse F. Abrams et al.1,915 citations
- Inactive (PbI 2 ) 2 RbCl stabilizes perovskite films for efficient solar cells ↗Yang Zhao, Fei Ma, Zihan Qu et al.1,445 citations
- Grassland soil carbon sequestration: Current understanding, challenges, and solutions ↗Yongfei Bai, M. Francesca Cotrufo1,356 citations
- CAR T cells produced in vivo to treat cardiac injury ↗Joel G. Rurik, István Tombácz, Amir Yadegari et al.1,353 citations
- Conformal quantum dot–SnO 2 layers as electron transporters for efficient perovskite solar cells ↗Minjin Kim, Jaeki Jeong, Haizhou Lu et al.1,346 citations
- Early detection of cancer ↗David L. Crosby, Sangeeta N. Bhatia, Kevin Michael Brindle et al.1,333 citations
- Cross-tissue immune cell analysis reveals tissue-specific features in humans ↗Cecilia Domínguez Conde, Chuan Xu, Lorna B. Jarvis et al.1,159 citations
- Tertiary lymphoid structures in cancer ↗Ton N. Schumacher, Daniela S. Thommen1,142 citations
- Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial ↗Peter B. Gilbert, David C. Montefiori, Adrian B. McDermott et al.1,135 citations
- High-entropy nanoparticles: Synthesis-structure-property relationships and data-driven discovery ↗Yonggang Yao, Qi Dong, Alexandra H. Brozena et al.1,071 citations
- The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans ↗Robert C. Jones, Jim Karkanias, Mark A. Krasnow et al.1,044 citations
- Organometallic-functionalized interfaces for highly efficient inverted perovskite solar cells ↗Zhen Li, Bo Li, Xin Wu et al.1,043 citations
- Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa ↗Juliet R.C. Pulliam, Cari van Schalkwyk, Nevashan Govender et al.1,032 citations
- Competition-level code generation with AlphaCodeYujia Li, David Choi, Junyoung Chung et al.1,016 citations · our summary
- Self-assembled monolayers direct a LiF-rich interphase toward long-life lithium metal batteries ↗Yujing Liu, Xinyong Tao, Yao Wang et al.962 citations
- Constructing heterojunctions by surface sulfidation for efficient inverted perovskite solar cells ↗Xiaodong Li, Wenxiao Zhang, Xuemin Guo et al.907 citations
- Damp heat–stable perovskite solar cells with tailored-dimensionality 2D/3D heterojunctions ↗Randi Azmi, Esma Ugur, Akmaral Seitkhan et al.855 citations
- Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly ↗Hongjie Li, Jasper Janssens, Maxime De Waegeneer et al.837 citations
- The biodiversity and ecosystem service contributions and trade-offs of forest restoration approaches ↗Fangyuan Hua, Leendert Adrian Bruijnzeel, Paula Meli et al.806 citations
- Designing better electrolytes ↗Ying Shirley Meng, Venkat N. Srinivasan, Kang Xu751 citations
- The immunology and immunopathology of COVID-19 ↗Miriam Mérad, Catherine A. Blish, Federica Sallusto et al.751 citations
- Machine learning–enabled high-entropy alloy discovery ↗Ziyuan Rao, Po‐Yen Tung, Ruiwen Xie et al.745 citations
- High figure-of-merit and power generation in high-entropy GeTe-based thermoelectrics ↗Binbin Jiang, Wu Wang, Shixuan Liu et al.729 citations
- Soil microbiota as game-changers in restoration of degraded lands ↗Oksana Coban, Gerlinde B. De Deyn, Martine J. van der Ploeg713 citations
- Memristive technologies for data storage, computation, encryption, and radio-frequency communication ↗Mario Lanza, Abu Sebastian, Wei Dong Lu et al.708 citations
- Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease ↗Seyhan Yazar, José Alquicira-Hernández, Kristof Wing et al.656 citations
- Microbiota and maintenance of skin barrier function ↗Tamia A. Harris-Tryon, Elizabeth A. Grice651 citations
- Mixed plastics waste valorization through tandem chemical oxidation and biological funneling ↗Kevin P. Sullivan, Allison Z. Werner, Kelsey J. Ramirez et al.635 citations
- SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex ↗Dhiraj Mannar, James W. Saville, Xing Quan Zhu et al.628 citations
- Chiral emission from resonant metasurfaces ↗Xudong Zhang, Yilin Liu, Jiecai Han et al.623 citations
- Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics ↗Yuanwen Jiang, Zhitao Zhang, Yi-Xuan Wang et al.617 citations
- Complete genomic and epigenetic maps of human centromeres ↗Nicolas Altemose, Glennis A. Logsdon, Andrey V. Bzikadze et al.601 citations
- Bioadhesive ultrasound for long-term continuous imaging of diverse organs ↗Chonghe Wang, Xiaoyu Chen, Liu Wang et al.599 citations
- Ultrahard magnetism from mixed-valence dilanthanide complexes with metal-metal bonding ↗Colin A. Gould, K. Randall McClain, Daniel Reta et al.596 citations
- Disentangling the numbers behind agriculture-driven tropical deforestation ↗Florence Pendrill, Toby Alan Gardner, Patrick Meyfroidt et al.564 citations
- Deterministic fabrication of 3D/2D perovskite bilayer stacks for durable and efficient solar cells ↗Siraj Sidhik, Yafei Wang, Michael C. De Siena et al.563 citations
- High-entropy mechanism to boost ionic conductivity ↗Yan Zeng, Bin Ouyang, Jue Liu et al.558 citations
- OpenCell: Endogenous tagging for the cartography of human cellular organization ↗Nathan H. Cho, Keith C. Cheveralls, Andreas‐David Brunner et al.557 citations
- Rethinking the A cation in halide perovskites ↗Jin‐Wook Lee, Shaun Wee Kiat Tan, Sang Il Seok et al.557 citations
- Cryo-EM structures of amyloid-β 42 filaments from human brains ↗Yang Yang, Diana Arseni, Wenjuan Zhang et al.549 citations
- Molecular basis of astrocyte diversity and morphology across the CNS in health and disease ↗Fumito Endo, Atsushi Kasai, Joselyn S. Soto et al.547 citations
- Big-data approaches lead to an increased understanding of the ecology of animal movement ↗Ran Nathan, Christopher T. Monk, Robert Arlinghaus et al.545 citations
- Exceptional fracture toughness of CrCoNi-based medium- and high-entropy alloys at 20 kelvin ↗Dong Liu, Qin Yu, Saurabh Kabra et al.543 citations
- Current global efforts are insufficient to limit warming to 1.5°C ↗H. Damon Matthews, Seth Wynes536 citations
- Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement ↗Matthew McCallum, Nadine Czudnochowski, Laura E. Rosen et al.534 citations
- Copper-induced cell death ↗Martha A. Kahlson, Scott J. Dixon521 citations
- Flexible thermoelectrics based on ductile semiconductors ↗Qingyu Yang, Shiqi Yang, Pengfei Qiu et al.518 citations
- Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus ↗Richard K. Perez, M. Grace Gordon, Meena Subramaniam et al.513 citations
- Quantum advantage in learning from experiments ↗Hsin-Yuan Huang, Michael Broughton, Jordan S. Cotler et al.511 citations
- Deep-learning seismology ↗S. Mostafa Mousavi, Gregory C. Beroza506 citations
- Covalent organic framework–based porous ionomers for high-performance fuel cells ↗Qingnuan Zhang, Shuda Dong, Pengpeng Shao et al.505 citations
- Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging ↗Michele Gabriele, Hugo B. Brandão, Simon Grosse‐Holz et al.501 citations
- Tissue geometry drives deterministic organoid patterning ↗Nikolche Gjorevski, Mikhail Nikolaev, Tobin E. Brown et al.499 citations
- Three-dimensional direct lithography of stable perovskite nanocrystals in glass ↗Ke Sun, Dezhi Tan, Xinyuan Fang et al.498 citations
- High-resolution mapping of losses and gains of Earth’s tidal wetlands ↗Nicholas Murray, Thomas A. Worthington, Peter Bunting et al.489 citations
- High-precision measurement of the W boson mass with the CDF II detector ↗T. Aaltonen, S. Amerio, D. Amidei et al.488 citations
- Capturing the swelling of solid-electrolyte interphase in lithium metal batteries ↗Zewen Zhang, Yuzhang Li, Rong Xu et al.486 citations
- Scaffolding protein functional sites using deep learning ↗Jue Wang, Sidney Lyayuga Lisanza, David Juergens et al.486 citations
- Evidence for neutrino emission from the nearby active galaxy NGC 1068 ↗R. Abbasi, M. Ackermann, Jenni Adams et al.472 citations
- Metastable Dion-Jacobson 2D structure enables efficient and stable perovskite solar cells ↗Fei Zhang, So Yeon Park, Canglang Yao et al.466 citations
- CDK4 and CDK6 kinases: From basic science to cancer therapy ↗Anne Fassl, Yan Geng, Piotr Siciński464 citations
- Efficient and stable perovskite-silicon tandem solar cells through contact displacement by MgF x ↗Jiang Liu, Michele De Bastiani, Erkan Aydın et al.460 citations
- High thermoelectric performance realized through manipulating layered phonon-electron decoupling ↗Lizhong Su, Dongyang Wang, Sining Wang et al.459 citations
- Piezoionic mechanoreceptors: Force-induced current generation in hydrogels ↗Yuta Dobashi, Dickson R. Yao, Yael Petel et al.457 citations
- Tunable structured light with flat optics ↗Ahmed H. Dorrah, Federico Capasso454 citations
- Engineering bacteria as interactive cancer therapies ↗Candice R. Gurbatri, Nicholas Arpaia, Tal Danino447 citations
- Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers ↗Frank J. Lowery, Sri Krishna, Rami Yossef et al.447 citations
- Controlling the nucleation and growth kinetics of lead halide perovskite quantum dots ↗Quinten A. Akkerman, Tan P. T. Nguyen, Simon Christian Boehme et al.446 citations
- Harnessing the potential of nature-based solutions for mitigating and adapting to climate change ↗Nathalie Seddon A445 citations
- Rapid changes to global river suspended sediment flux by humans ↗Evan Nylen Dethier, Carl Edward Renshaw, Francis J. Magilligan442 citations
- Rational design of mixed-matrix metal-organic framework membranes for molecular separations ↗Shuvo Jit Datta, Álvaro Mayoral, N.M. Srivatsa Bettahalli et al.440 citations
- Nervous system consequences of COVID-19 ↗Serena Spudich, Avindra Nath435 citations
- The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic ↗Michael Worobey, Joshua I. Levy, Lorena M. Malpica Serrano et al.435 citations
- Ion-modulated radical doping of spiro-OMeTAD for more efficient and stable perovskite solar cells ↗Tiankai Zhang, Feng Wang, Hak‐Beom Kim et al.432 citations
- Universal assembly of liquid metal particles in polymers enables elastic printed circuit board ↗Wonbeom Lee, Hyunjun Kim, In-Ho Kang et al.430 citations
- A complete reference genome improves analysis of human genetic variation ↗Sergey S. Aganezov, Stephanie M. Yan, Daniela C. Soto et al.429 citations
- The emergent properties of the connected brain ↗Michel Thiebaut de Schotten, Stephanie J. Forkel429 citations
- The microbiome and gut homeostasis ↗Jee‐Yon Lee, Renée M. Tsolis, Andreas J. Bäumler428 citations
- Compositional texture engineering for highly stable wide-bandgap perovskite solar cells ↗Qi Jiang, Jinhui Tong, Rebecca A. Scheidt et al.425 citations
- Quantum optimization of maximum independent set using Rydberg atom arrays ↗Sepehr Ebadi, Alexander Keesling, Madelyn Cain et al.424 citations
- Global assessment of oil and gas methane ultra-emitters ↗Thomas Lauvaux, Clément Giron, Matthieu Mazzolini et al.423 citations
- Catalytic deconstruction of waste polyethylene with ethylene to form propylene ↗Richard J. Conk, Steven Hanna, Jake X. Shi et al.419 citations
- Grazing and ecosystem service delivery in global drylands ↗Fernando T. Maestre, Yoann Le Bagousse‐Pinguet, Manuel Delgado‐Baquerizo et al.419 citations
- Multispecies forest plantations outyield monocultures across a broad range of conditions ↗Yuhao Feng, Bernhard Schmid, Michel Loreau et al.419 citations
- Low-temperature mineralization of perfluorocarboxylic acids ↗Brittany Trang, Yuli Li, Xiao‐Song Xue et al.418 citations
- Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function ↗Gökçen Eraslan, Eugene Drokhlyansky, Shankara K. Anand et al.405 citations
- From telomere to telomere: The transcriptional and epigenetic state of human repeat elements ↗Savannah J. Hoyt, Jessica M. Storer, Gabrielle A. Hartley et al.403 citations
- Late-stage diversification of indole skeletons through nitrogen atom insertion ↗Julia C. Reisenbauer, Ori Green, Allegra Franchino et al.395 citations
- A photonic integrated circuit–based erbium-doped amplifier ↗Yang Liu, Zheru Qiu, Xinru Ji et al.390 citations
- Dynamic interplay between metal nanoparticles and oxide support under redox conditions ↗Hannes Frey, Arik Beck, Xing Huang et al.390 citations
- Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level ↗Yanxiang Deng, Marek Bartošovič, Petra Kukanja et al.388 citations
- Highly flexible and superhydrophobic MOF nanosheet membrane for ultrafast alcohol-water separation ↗Li‐Hao Xu, Shen-Hui Li, Heng Mao et al.382 citations
- Isospin magnetism and spin-polarized superconductivity in Bernal bilayer graphene ↗Haoxin Zhou, Ludwig Holleis, Yu Saito et al.378 citations
- Recovering wetland biogeomorphic feedbacks to restore the world’s biotic carbon hotspots ↗Ralph J. M. Temmink, Leon P. M. Lamers, Christine Angelini et al.378 citations
- Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera ↗Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch et al.367 citations
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