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Science 2022: all accepted papers

2,047 papers · page 1 of 21 · the most cited first · ← Science 2022

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  1. Copper induces cell death by targeting lipoylated TCA cycle proteins ↗Peter Tsvetkov, Shannon Coy, Boryana Petrova et al.4,849 citations
  2. The complete sequence of a human genome ↗Sergey Nurk, Sergey Koren, Arang Rhie et al.3,060 citations
  3. Per- and polyfluoroalkyl substances in the environment ↗Marina G. Evich, Mary J. B. Davis, James P. McCord et al.2,106 citations
  4. Robust deep learning–based protein sequence design using ProteinMPNN ↗Justas Dauparas, Ivan V. Anishchenko, Nathaniel R. Bennett et al.2,051 citations
  5. Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis ↗Kjetil Bjørnevik, Marianna Cortese, Brian C. Healy et al.2,027 citations
  6. Exceeding 1.5°C global warming could trigger multiple climate tipping points ↗David I. Armstrong McKay, Arie Staal, Jesse F. Abrams et al.1,915 citations
  7. CAR T cells produced in vivo to treat cardiac injury ↗Joel G. Rurik, István Tombácz, Amir Yadegari et al.1,353 citations
  8. Early detection of cancer ↗David L. Crosby, Sangeeta N. Bhatia, Kevin Michael Brindle et al.1,333 citations
  9. Cross-tissue immune cell analysis reveals tissue-specific features in humans ↗Cecilia Domínguez Conde, Chuan Xu, Lorna B. Jarvis et al.1,159 citations
  10. Tertiary lymphoid structures in cancer ↗Ton N. Schumacher, Daniela S. Thommen1,142 citations
  11. Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial ↗Peter B. Gilbert, David C. Montefiori, Adrian B. McDermott et al.1,135 citations
  12. The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans ↗Robert C. Jones, Jim Karkanias, Mark A. Krasnow et al.1,044 citations
  13. Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa ↗Juliet R.C. Pulliam, Cari van Schalkwyk, Nevashan Govender et al.1,032 citations
  14. Competition-level code generation with AlphaCodeYujia Li, David Choi, Junyoung Chung et al.1,016 citations · our summary
  15. Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly ↗Hongjie Li, Jasper Janssens, Maxime De Waegeneer et al.837 citations
  16. The biodiversity and ecosystem service contributions and trade-offs of forest restoration approaches ↗Fangyuan Hua, Leendert Adrian Bruijnzeel, Paula Meli et al.806 citations
  17. Designing better electrolytes ↗Ying Shirley Meng, Venkat N. Srinivasan, Kang Xu751 citations
  18. The immunology and immunopathology of COVID-19 ↗Miriam Mérad, Catherine A. Blish, Federica Sallusto et al.751 citations
  19. Machine learning–enabled high-entropy alloy discovery ↗Ziyuan Rao, Po‐Yen Tung, Ruiwen Xie et al.745 citations
  20. Soil microbiota as game-changers in restoration of degraded lands ↗Oksana Coban, Gerlinde B. De Deyn, Martine J. van der Ploeg713 citations
  21. Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease ↗Seyhan Yazar, José Alquicira-Hernández, Kristof Wing et al.656 citations
  22. Microbiota and maintenance of skin barrier function ↗Tamia A. Harris-Tryon, Elizabeth A. Grice651 citations
  23. Mixed plastics waste valorization through tandem chemical oxidation and biological funneling ↗Kevin P. Sullivan, Allison Z. Werner, Kelsey J. Ramirez et al.635 citations
  24. Chiral emission from resonant metasurfaces ↗Xudong Zhang, Yilin Liu, Jiecai Han et al.623 citations
  25. Complete genomic and epigenetic maps of human centromeres ↗Nicolas Altemose, Glennis A. Logsdon, Andrey V. Bzikadze et al.601 citations
  26. Bioadhesive ultrasound for long-term continuous imaging of diverse organs ↗Chonghe Wang, Xiaoyu Chen, Liu Wang et al.599 citations
  27. Ultrahard magnetism from mixed-valence dilanthanide complexes with metal-metal bonding ↗Colin A. Gould, K. Randall McClain, Daniel Reta et al.596 citations
  28. Disentangling the numbers behind agriculture-driven tropical deforestation ↗Florence Pendrill, Toby Alan Gardner, Patrick Meyfroidt et al.564 citations
  29. High-entropy mechanism to boost ionic conductivity ↗Yan Zeng, Bin Ouyang, Jue Liu et al.558 citations
  30. OpenCell: Endogenous tagging for the cartography of human cellular organization ↗Nathan H. Cho, Keith C. Cheveralls, Andreas‐David Brunner et al.557 citations
  31. Rethinking the A cation in halide perovskites ↗Jin‐Wook Lee, Shaun Wee Kiat Tan, Sang Il Seok et al.557 citations
  32. Cryo-EM structures of amyloid-β 42 filaments from human brains ↗Yang Yang, Diana Arseni, Wenjuan Zhang et al.549 citations
  33. Molecular basis of astrocyte diversity and morphology across the CNS in health and disease ↗Fumito Endo, Atsushi Kasai, Joselyn S. Soto et al.547 citations
  34. Big-data approaches lead to an increased understanding of the ecology of animal movement ↗Ran Nathan, Christopher T. Monk, Robert Arlinghaus et al.545 citations
  35. Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement ↗Matthew McCallum, Nadine Czudnochowski, Laura E. Rosen et al.534 citations
  36. Copper-induced cell death ↗Martha A. Kahlson, Scott J. Dixon521 citations
  37. Flexible thermoelectrics based on ductile semiconductors ↗Qingyu Yang, Shiqi Yang, Pengfei Qiu et al.518 citations
  38. Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus ↗Richard K. Perez, M. Grace Gordon, Meena Subramaniam et al.513 citations
  39. Quantum advantage in learning from experiments ↗Hsin-Yuan Huang, Michael Broughton, Jordan S. Cotler et al.511 citations
  40. Deep-learning seismology ↗S. Mostafa Mousavi, Gregory C. Beroza506 citations
  41. Covalent organic framework–based porous ionomers for high-performance fuel cells ↗Qingnuan Zhang, Shuda Dong, Pengpeng Shao et al.505 citations
  42. Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging ↗Michele Gabriele, Hugo B. Brandão, Simon Grosse‐Holz et al.501 citations
  43. Tissue geometry drives deterministic organoid patterning ↗Nikolche Gjorevski, Mikhail Nikolaev, Tobin E. Brown et al.499 citations
  44. High-resolution mapping of losses and gains of Earth’s tidal wetlands ↗Nicholas Murray, Thomas A. Worthington, Peter Bunting et al.489 citations
  45. High-precision measurement of the W boson mass with the CDF II detector ↗T. Aaltonen, S. Amerio, D. Amidei et al.488 citations
  46. Scaffolding protein functional sites using deep learning ↗Jue Wang, Sidney Lyayuga Lisanza, David Juergens et al.486 citations
  47. Evidence for neutrino emission from the nearby active galaxy NGC 1068 ↗R. Abbasi, M. Ackermann, Jenni Adams et al.472 citations
  48. CDK4 and CDK6 kinases: From basic science to cancer therapy ↗Anne Fassl, Yan Geng, Piotr Siciński464 citations
  49. Piezoionic mechanoreceptors: Force-induced current generation in hydrogels ↗Yuta Dobashi, Dickson R. Yao, Yael Petel et al.457 citations
  50. Tunable structured light with flat optics ↗Ahmed H. Dorrah, Federico Capasso454 citations
  51. Engineering bacteria as interactive cancer therapies ↗Candice R. Gurbatri, Nicholas Arpaia, Tal Danino447 citations
  52. Controlling the nucleation and growth kinetics of lead halide perovskite quantum dots ↗Quinten A. Akkerman, Tan P. T. Nguyen, Simon Christian Boehme et al.446 citations
  53. Rapid changes to global river suspended sediment flux by humans ↗Evan Nylen Dethier, Carl Edward Renshaw, Francis J. Magilligan442 citations
  54. Rational design of mixed-matrix metal-organic framework membranes for molecular separations ↗Shuvo Jit Datta, Álvaro Mayoral, N.M. Srivatsa Bettahalli et al.440 citations
  55. Nervous system consequences of COVID-19 ↗Serena Spudich, Avindra Nath435 citations
  56. The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic ↗Michael Worobey, Joshua I. Levy, Lorena M. Malpica Serrano et al.435 citations
  57. A complete reference genome improves analysis of human genetic variation ↗Sergey S. Aganezov, Stephanie M. Yan, Daniela C. Soto et al.429 citations
  58. The emergent properties of the connected brain ↗Michel Thiebaut de Schotten, Stephanie J. Forkel429 citations
  59. The microbiome and gut homeostasis ↗Jee‐Yon Lee, Renée M. Tsolis, Andreas J. Bäumler428 citations
  60. Compositional texture engineering for highly stable wide-bandgap perovskite solar cells ↗Qi Jiang, Jinhui Tong, Rebecca A. Scheidt et al.425 citations
  61. Quantum optimization of maximum independent set using Rydberg atom arrays ↗Sepehr Ebadi, Alexander Keesling, Madelyn Cain et al.424 citations
  62. Global assessment of oil and gas methane ultra-emitters ↗Thomas Lauvaux, Clément Giron, Matthieu Mazzolini et al.423 citations
  63. Catalytic deconstruction of waste polyethylene with ethylene to form propylene ↗Richard J. Conk, Steven Hanna, Jake X. Shi et al.419 citations
  64. Grazing and ecosystem service delivery in global drylands ↗Fernando T. Maestre, Yoann Le Bagousse‐Pinguet, Manuel Delgado‐Baquerizo et al.419 citations
  65. Multispecies forest plantations outyield monocultures across a broad range of conditions ↗Yuhao Feng, Bernhard Schmid, Michel Loreau et al.419 citations
  66. Low-temperature mineralization of perfluorocarboxylic acids ↗Brittany Trang, Yuli Li, Xiao‐Song Xue et al.418 citations
  67. Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function ↗Gökçen Eraslan, Eugene Drokhlyansky, Shankara K. Anand et al.405 citations
  68. From telomere to telomere: The transcriptional and epigenetic state of human repeat elements ↗Savannah J. Hoyt, Jessica M. Storer, Gabrielle A. Hartley et al.403 citations
  69. Late-stage diversification of indole skeletons through nitrogen atom insertion ↗Julia C. Reisenbauer, Ori Green, Allegra Franchino et al.395 citations
  70. A photonic integrated circuit–based erbium-doped amplifier ↗Yang Liu, Zheru Qiu, Xinru Ji et al.390 citations
  71. Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level ↗Yanxiang Deng, Marek Bartošovič, Petra Kukanja et al.388 citations
  72. Isospin magnetism and spin-polarized superconductivity in Bernal bilayer graphene ↗Haoxin Zhou, Ludwig Holleis, Yu Saito et al.378 citations
  73. Recovering wetland biogeomorphic feedbacks to restore the world’s biotic carbon hotspots ↗Ralph J. M. Temmink, Leon P. M. Lamers, Christine Angelini et al.378 citations
  74. Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera ↗Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch et al.367 citations

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