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Science 2012: all accepted papers

4,169 papers · page 1 of 42 · the most cited first · ← Science 2012

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  1. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity ↗Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al.17,051 citations
  2. Efficient Hybrid Solar Cells Based on Meso-Superstructured Organometal Halide Perovskites ↗Michael M. Lee, Joël Teuscher, Tsutomu Miyasaka et al.10,668 citations
  3. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway ↗Lijun Sun, Jiaxi Wu, Fenghe Du et al.4,925 citations
  4. Host-Gut Microbiota Metabolic Interactions ↗Jeremy Kirk Nicholson, Elaine C. Holmes, James K. Kinross et al.4,725 citations
  5. Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs ↗Lihong V. Wang, Song Hu4,297 citations
  6. Interactions Between the Microbiota and the Immune System ↗Lora V. Hooper, Dan R. Littman, Andrew J. Macpherson4,162 citations
  7. Signatures of Majorana Fermions in Hybrid Superconductor-Semiconductor Nanowire Devices ↗Vincent Mourik, K. Zuo, Sergey Frolov et al.4,155 citations
  8. Spin-Torque Switching with the Giant Spin Hall Effect of Tantalum ↗Luqiao Liu, Chi‐Feng Pai, Y. Li et al.4,108 citations
  9. Laser Scribing of High-Performance and Flexible Graphene-Based Electrochemical Capacitors ↗Maher F. El‐Kady, Veronica Strong, Sergey Dubin et al.4,008 citations
  10. Functional Supramolecular Polymers ↗Takuzo Aida, Egbert W. Meijer, Samuel Isaac Stupp3,696 citations
  11. Systematic Localization of Common Disease-Associated Variation in Regulatory DNA ↗Matthew T. Maurano, Richard Humbert, Eric Rynes et al.3,692 citations
  12. Mitochondrial Fission, Fusion, and Stress ↗Richard J. Youle, Alexander M. van der Bliek3,645 citations
  13. Unimpeded Permeation of Water Through Helium-Leak–Tight Graphene-Based Membranes ↗Rahul R. Nair, HengAn Wu, P. N. Jayaram et al.3,073 citations
  14. The Active Site of Methanol Synthesis over Cu/ZnO/Al 2 O 3 Industrial Catalysts ↗Malte Behrens, Felix Studt, Igor Kasatkin et al.2,670 citations
  15. A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells ↗Christian Schulz, Elisa Gomez Perdiguero, Laurent Chorro et al.2,568 citations
  16. Field-Effect Tunneling Transistor Based on Vertical Graphene Heterostructures ↗L. Britnell, Roman Gorbachev, R. Jalil et al.2,561 citations
  17. Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice ↗Kelvin C. Luk, Victoria M. Kehm, Jenna C. Carroll et al.2,545 citations
  18. Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA ↗Jiaxi Wu, Lijun Sun, Xiang Chen et al.2,541 citations
  19. Detecting Causality in Complex Ecosystems ↗George Sugihara, Robert Mccredie May, Hao Ye et al.2,539 citations
  20. Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota ↗Janelle C. Arthur, Ernesto Peréz-Chanona, Marcus Mühlbauer et al.2,251 citations
  21. The State and Fate of Himalayan Glaciers ↗Tobias Bolch, Anil Vishnupant Kulkarni, Andreas Kääb et al.2,207 citations
  22. Anticipating Critical Transitions ↗Marten Scheffer, Stephen R. Carpenter, Timothy M. Lenton et al.2,192 citations
  23. A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads ↗Shawn M. Douglas, Ido Bachelet, George McDonald Church2,180 citations
  24. Valorization of Biomass: Deriving More Value from Waste ↗Christopher J. Tuck, Eduardo Pérez, István T. Horváth et al.2,165 citations
  25. A Universal Method to Produce Low–Work Function Electrodes for Organic Electronics ↗Yinhua Zhou, Canek Fuentes‐Hernandez, Jaewon Shim et al.2,140 citations
  26. Large-Pore Apertures in a Series of Metal-Organic Frameworks ↗Hexiang Deng, Sergio Grunder, Kyle E. Cordova et al.2,126 citations
  27. Binary Interaction Dominates the Evolution of Massive Stars ↗Hugues Sana, S. E. de Mink, A. de Koter et al.2,118 citations
  28. A High-Coverage Genome Sequence from an Archaic Denisovan Individual ↗Matthias Meyer, Martin Kircher, Marie-Theres Gansauge et al.1,961 citations
  29. Hydrocarbon Separations in a Metal-Organic Framework with Open Iron(II) Coordination Sites ↗Eric D. Bloch, Wendy Lee Queen, Rajamani Krishna et al.1,928 citations
  30. Designing Cell-Compatible Hydrogels for Biomedical Applications ↗Dror Seliktar1,923 citations
  31. A Reversible and Higher-Rate Li-O 2 Battery ↗Zhangquan Peng, Stefan A. Freunberger, Yuhui Chen et al.1,915 citations
  32. Conversion of Wastes into Bioelectricity and Chemicals by Using Microbial Electrochemical Technologies ↗Bruce E. Logan, Korneel Rabaey1,877 citations
  33. Bright Coherent Ultrahigh Harmonics in the keV X-ray Regime from Mid-Infrared Femtosecond Lasers ↗Tenio Popmintchev, Ming-Chang Chen, Dimitar Popmintchev et al.1,829 citations
  34. The Paleozoic Origin of Enzymatic Lignin Decomposition Reconstructed from 31 Fungal Genomes ↗Dimitrios Floudas, Manfred Binder, Robert W. Riley et al.1,779 citations
  35. Linking Crystallographic Model and Data Quality ↗P. Andrew Karplus, Kay Diederichs1,774 citations
  36. Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor ↗Tadahiro Shimazu, Matthew D. Hirschey, John Newman et al.1,762 citations
  37. Plant Species Richness and Ecosystem Multifunctionality in Global Drylands ↗Fernando T. Maestre, José Luis Quero, Nicholas J. Gotelli et al.1,718 citations
  38. Disease Tolerance as a Defense Strategy ↗Ruslan M. Medzhitov, David S. Schneider, Miguel Parreira Soares1,702 citations
  39. The Protein-Folding Problem, 50 Years On ↗Ken A. Dill, Justin L. MacCallum1,693 citations
  40. Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets ↗Sander Herfst, Eefje J. A. Schrauwen, Martin Linster et al.1,665 citations
  41. Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function ↗Torsten Olszak, Dingding An, Sebastian Zeißig et al.1,660 citations
  42. The Shared Antibiotic Resistome of Soil Bacteria and Human Pathogens ↗Kevin J. Forsberg, Alejandro Reyes, Bin Wang et al.1,645 citations
  43. Synaptic Dysfunction in Depression: Potential Therapeutic Targets ↗Ronald S. Duman, George K. Aghajanian1,637 citations
  44. Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes ↗Jacob Adam Tennessen, Abigail W. Bigham, Timothy D. O’Connor et al.1,611 citations
  45. Isolated Metal Atom Geometries as a Strategy for Selective Heterogeneous Hydrogenations ↗Georgios Kyriakou, Matthew B. Boucher, April D. Jewell et al.1,603 citations
  46. Some Consequences of Having Too Little ↗Anuj Shah, Sendhil Mullainathan, Eldar B. Shafir1,551 citations
  47. A Reconciled Estimate of Ice-Sheet Mass Balance ↗Andrew P. Shepherd, Erik R. Ivins, A Geruo et al.1,511 citations
  48. A Common Pesticide Decreases Foraging Success and Survival in Honey Bees ↗Mickaël Henry, Maxime Béguin, Fabrice Réquier et al.1,474 citations
  49. Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals ↗Nobuya Koike, Seung Hee Yoo, Hung-Chung Huang et al.1,458 citations
  50. The Application of Ecological Theory Toward an Understanding of the Human Microbiome ↗Elizabeth K. Costello, Keaton Stagaman, Les Dethlefsen et al.1,437 citations
  51. Next-Generation Digital Information Storage in DNA ↗George McDonald Church, Yuan Gao, Sriram Kosuri1,428 citations
  52. Substrate-Controlled Succession of Marine Bacterioplankton Populations Induced by a Phytoplankton Bloom ↗Hanno Teeling, Bernhard Maximilian Fuchs, Dörte Becher et al.1,422 citations
  53. An Update of Wallace’s Zoogeographic Regions of the World ↗Ben G. Holt, Jean‐Philippe Lessard, Michael K. Borregaard et al.1,414 citations
  54. Observation of Skyrmions in a Multiferroic Material ↗Shinichiro Seki, Xiuzhen Yu, Shintaro Ishiwata et al.1,413 citations
  55. Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation ↗Mohit Jain, Roland Nilsson, Sonia Sharma et al.1,401 citations
  56. Simultaneously Mitigating Near-Term Climate Change and Improving Human Health and Food Security ↗Drew T. Shindell, Johan C.I. Kuylenstierna, E. Vignati et al.1,374 citations
  57. Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities ↗Zhiliang Cheng, Ajlan Al Zaki, James Z. Hui et al.1,322 citations
  58. A Local Proton Source Enhances CO 2 Electroreduction to CO by a Molecular Fe Catalyst ↗Cyrille Costentin, Samuel Drouet, Marc Robert et al.1,315 citations
  59. Neonicotinoid Pesticide Reduces Bumble Bee Colony Growth and Queen Production ↗Penelope R. Whitehorn, Stephanie O’Connor, FELIX L. WÄCKERS et al.1,290 citations
  60. A Physically Transient Form of Silicon Electronics ↗Suk‐Won Hwang, Hu Tao, Dae‐Hyeong Kim et al.1,277 citations
  61. A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes ↗Daniel G. MacArthur, Suganthi Balasubramanian, Adam Frankish et al.1,270 citations
  62. Epigenetic Regulation by Long Noncoding RNAs ↗Jeannie T. Lee1,259 citations
  63. Network Interventions ↗Thomas William Valente1,248 citations
  64. The Diffusion of Microfinance ↗Abhijit Banerjee, Arun G. Chandrasekhar, Esther Duflo et al.1,248 citations
  65. Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons ↗Ke Xu, Guisheng Zhong, Xiaowei Zhuang1,246 citations
  66. Three-Dimensional Structures Self-Assembled from DNA Bricks ↗Yonggang Ke, Luvena L. Ong, William M. Shih et al.1,246 citations
  67. Supported Iron Nanoparticles as Catalysts for Sustainable Production of Lower Olefins ↗Hirsa M. Torres Galvis, Johannes Hendrik Bitter, Chaitanya B. Khare et al.1,244 citations
  68. Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders ↗Brian J. O’Roak, Laura Vives, Wenqing Fu et al.1,237 citations
  69. A Molecular MoS 2 Edge Site Mimic for Catalytic Hydrogen Generation ↗Hemamala I. Karunadasa, E. Montalvo, Yujie Sun et al.1,212 citations
  70. Female Leadership Raises Aspirations and Educational Attainment for Girls: A Policy Experiment in India ↗Lori A. Beaman, Esther Duflo, Rohini Pande et al.1,205 citations
  71. Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity ↗Dudley W. Lamming, Lan Ye, Pekka Katajisto et al.1,195 citations
  72. The Role of Driving Energy and Delocalized States for Charge Separation in Organic Semiconductors ↗Artem A. Bakulin, Akshay Rao, Vlad G. Pavelyev et al.1,182 citations
  73. Unlike Bone, Cartilage Regeneration Remains Elusive ↗Daniel J. Huey, Jerry C. Y. Hu, Kyriacos A. Athanasiou1,182 citations
  74. Lethally Hot Temperatures During the Early Triassic Greenhouse ↗Yadong Sun, Michael M. Joachimski, Paul B. Wignall et al.1,175 citations
  75. Probing the Ultimate Limits of Plasmonic Enhancement ↗Cristian Ciracì, Ryan T. Hill, Jack J. Mock et al.1,172 citations
  76. Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell ↗Chenghang Zong, Sijia Lü, Alec R. Chapman et al.1,153 citations
  77. High-Resolution EM of Colloidal Nanocrystal Growth Using Graphene Liquid Cells ↗Jong Min Yuk, Jungwon Park, Peter A. Ercius et al.1,153 citations
  78. Multiblock Polymers: Panacea or Pandora’s Box? ↗Frank S. Bates, Marc A. Hillmyer, Timothy P. Lodge et al.1,142 citations
  79. Direction-Specific Interactions Control Crystal Growth by Oriented Attachment ↗Dongsheng Li, Michael H. Nielsen, Jonathan R. I. Lee et al.1,120 citations
  80. Long-Range Incommensurate Charge Fluctuations in (Y,Nd)Ba 2 Cu 3 O 6+ x ↗Giacomo Claudio Ghiringhelli, M. Le Tacon, M. Minola et al.1,113 citations
  81. Printing and Prototyping of Tissues and Scaffolds ↗Brian Derby1,108 citations
  82. Predictive Self-Assembly of Polyhedra into Complex Structures ↗Pablo F. Damasceno, Michael Engel, Sharon C. Glotzer1,095 citations
  83. Superconducting Dome in a Gate-Tuned Band Insulator ↗J. T. Ye, Yijin Zhang, Ryosuke Akashi et al.1,088 citations
  84. Compartmentalized Control of Skin Immunity by Resident Commensals ↗Shruti Naik, Nicolas Jean Bouladoux, Christoph Wilhelm et al.1,087 citations
  85. Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis ↗Iliyan Dimitrov Iliev, Vincent Anthony Funari, Kent D. Taylor et al.1,072 citations
  86. Lineage Tracing Reveals Lgr5 + Stem Cell Activity in Mouse Intestinal Adenomas ↗Arnout G. Schepers, Hugo J.G. Snippert, Daniel E. Stange et al.1,072 citations
  87. Ocean Salinities Reveal Strong Global Water Cycle Intensification During 1950 to 2000 ↗Paul J. Durack, Susan Wijffels, Richard J. Matear1,067 citations
  88. Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation ↗Amrita M. Nargund, Mark W. Pellegrino, Christopher J. Fiorese et al.1,059 citations
  89. The Evolutionary Landscape of Alternative Splicing in Vertebrate Species ↗Nuno L. Barbosa‐Morais, Manuel Irimia, Qun Pan et al.1,059 citations
  90. The Geological Record of Ocean Acidification ↗Bärbel Hönisch, Andy J. Ridgwell, Daniela N. Schmidt et al.1,056 citations
  91. Relaxation and Prethermalization in an Isolated Quantum System ↗Michael Gring, Maximilian Kuhnert, Tim Langen et al.1,047 citations
  92. ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models ↗Paige E. Cramer, John R. Cirrito, Daniel W. Wesson et al.1,045 citations
  93. Identifying Influential and Susceptible Members of Social Networks ↗Sinan Aral, Dylan Walker1,042 citations
  94. Exceptional Activity for Methane Combustion over Modular Pd@CeO 2 Subunits on Functionalized Al 2 O 3 ↗Matteo Cargnello, J. J. Delgado Jaén, Juan Carlos Hernández‐Garrido et al.1,023 citations
  95. The Pulvinar Regulates Information Transmission Between Cortical Areas Based on Attention Demands ↗Yuri B. Saalmann, Mark A. Pinsk, Liang Wang et al.1,013 citations
  96. Quantifying the Impact of Human Mobility on Malaria ↗Amy Wesolowski, Nathan Eagle, Andrew J. Tatem et al.989 citations
  97. The Crust of the Moon as Seen by GRAIL ↗Mark A. Wieczorek, Gregory A. Neumann, F. Nimmo et al.976 citations
  98. Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues ↗Jason J. Merkin, Caitlin R. Russell, Ping Chen et al.968 citations
  99. Recent Plant Diversity Changes on Europe’s Mountain Summits ↗Harald Pauli, Michael Gottfried, Stefan Dullinger et al.962 citations
  100. Graphene Barristor, a Triode Device with a Gate-Controlled Schottky Barrier ↗Heejun Yang, Jinseong Heo, Seongjun Park et al.961 citations

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