Proceedings of the National Academy of Sciences 2024: all accepted papers
- Successful use of anti-CD19 CAR T cells in severe treatment-refractory stiff-person syndrome ↗Simon Faissner, Jeremias Motte, Melissa Sgodzai et al.76 citations
- The Warburg Effect is the result of faster ATP production by glycolysis than respiration ↗Matthew A. Kukurugya, Saharon Rosset, Denis V. Titov76 citations
- AlphaFold two years on: Validation and impact ↗Oleg V. Kovalevskiy, Juan C Mateos-Garcia, Kathryn Tunyasuvunakool75 citations
- Stabilizing Ti 3 C 2 T x MXene flakes in air by removing confined water ↗Hui Fang, Anupma Thakur, Amirhossein Zahmatkeshsaredorahi et al.75 citations
- iATPSnFR2: A high-dynamic-range fluorescent sensor for monitoring intracellular ATP ↗Jonathan S. Marvin, Alexandros C. Kokotos, Mukesh Kumar et al.75 citations
- Global emergence of regional heatwave hotspots outpaces climate model simulations ↗Kai Kornhuber, Samuel Bartusek, Richard Seager et al.74 citations
- Mineral-associated organic matter is heterogeneous and structured by hydrophobic, charged, and polar interactions ↗Thomas R. Underwood, Ian C. Bourg, Kevin M. Rosso74 citations
- Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2 ↗Heike Schönherr, Pelin Ayaz, Alexander M. Taylor et al.73 citations
- Heterogeneity in effect size estimates ↗Felix Holzmeister, Magnus Johannesson, ROBERT M. BOHM et al.73 citations
- The IRG1–itaconate axis protects from cholesterol-induced inflammation and atherosclerosis ↗Yannick Cyr, Fazli K. Bozal, José Gabriel Barcia Durán et al.73 citations
- Trends in US public confidence in science and opportunities for progress ↗Arthur Lupia, David Blair Allison, Kathleen Hall Jamieson et al.73 citations
- Spatially resolved land and grid model of carbon neutrality in China ↗Da Zhang, Ziheng Zhu, Shi Chen et al.72 citations
- Tailoring the selective generation of oxidative organic radicals for toxic-by-product-free water decontamination ↗Jing‐Hang Wu, Tianhao Yang, Yi-Jiao Sun et al.72 citations
- The microbiota-dependent tryptophan metabolite alleviates high-fat diet–induced insulin resistance through the hepatic AhR/TSC2/mTORC1 axis ↗Wei Du, Shanshan Jiang, SN Yin et al.72 citations
- Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery ↗Zhao Gan, Lulu Xue, Hannah C. Geisler et al.71 citations
- Regulation of the d-band center of metal–organic frameworks for energy-saving hydrogen generation coupled with selective glycerol oxidation ↗Yuqian He, Zheng Ma, Feng Yan et al.71 citations
- Superoxide radicals mediated by high-spin Fe catalysis for organic wastewater treatment ↗Yanxiao Li, Dongpeng Zhang, Pengfei Wang et al.71 citations
- Copper regulates the host innate immune response against bacterial infection via activation of ALPK1 kinase ↗Jing Lu, Xue Liu, Xinghua Li et al.70 citations
- TULIP: A transformer-based unsupervised language model for interacting peptides and T cell receptors that generalizes to unseen epitopes ↗Barthelemy Meynard-Piganeau, Christoph Feinauer, Martin Weigt et al.70 citations
- The m 6 A reader SlYTH2 negatively regulates tomato fruit aroma by impeding the translation process ↗Hanxiao Bian, Peizhe Song, Ying Gao et al.69 citations
- Brighter nights and darker days predict higher mortality risk: A prospective analysis of personal light exposure in >88,000 individuals ↗Daniel P. Windred, Angus C. Burns, Jacqueline M. Lane et al.68 citations
- Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis ↗Takehiko Oami, Shabnam Abtahi, Takashi Shimazui et al.68 citations
- Adaptive expression of phage auxiliary metabolic genes in paddy soils and their contribution toward global carbon sequestration ↗Dong Zhu, Shuyue Liu, Mingming Sun et al.66 citations
- Lipid shape and packing are key for optimal design of pH-sensitive mRNA lipid nanoparticles ↗Giulio Tesei, Ya‐Wen Hsiao, Aleksandra P. Dabkowska et al.66 citations
- N-degron pathways ↗Alexander J. Varshavsky66 citations
- ChatGPT as Research Scientist: Probing GPT’s capabilities as a Research Librarian, Research Ethicist, Data Generator, and Data Predictor ↗Steven A. Lehr, Aylin Caliskan, Suneragiri Liyanage et al.65 citations
- Engineering peroxisomal biosynthetic pathways for maximization of triterpene production in Yarrowia lipolytica ↗Yongshuo Ma, Yi Shang, Gregory N Stephanopoulos65 citations
- Multiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma ↗Clarisse Gânier, Pavel Mazin, Gabriel Emilio Herrera-Oropeza et al.65 citations
- The perivascular space is a conduit for cerebrospinal fluid flow in humans: A proof-of-principle report ↗Erin A. Yamamoto, Jacob H. Bagley, Mathew N. Geltzeiler et al.65 citations
- Climate change determines the sign of productivity trends in US forests ↗J. Aaron Hogan, Grant M. Domke, Kai Zhu et al.64 citations
- Positive associations fuel soil biodiversity and ecological networks worldwide ↗Xu Liu, Haiyan Chu, Óscar Godoy et al.64 citations
- The CRL3 KCTD10 ubiquitin ligase–USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11 ↗Qiyin Zhou, Hongfei Yu, Yongxia Chen et al.64 citations
- Three-atom-wide gold quantum rods with periodic elongation and strongly polarized excitons ↗Lianshun Luo, Zhongyu Liu, Jie Kong et al.64 citations
- A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells ↗Jade Harkin, Kiersten H. Peña, Cátia Gomes et al.63 citations
- Accelerating diabetic wound healing by ROS-scavenging lipid nanoparticle–mRNA formulation ↗Siyu Wang, Yuebao Zhang, Yichen Zhong et al.63 citations
- Climate migration amplifies demographic change and population aging ↗Mathew E. Hauer, Sunshine A. Jacobs, Scott Kulp63 citations
- Enriching surface-ordered defects on WO 3 for photocatalytic CO 2 -to-CH 4 conversion by water ↗Sikang Xue, Changgeng Wei, Min Shen et al.63 citations
- Lipid scrambling is a general feature of protein insertases ↗Dazhi Li, Cristian Rocha‐Roa, Matthew Aaron Schilling et al.63 citations
- Rubisco is evolving for improved catalytic efficiency and CO 2 assimilation in plants ↗Jacques W. Bouvier, David Emms, Steven L. Kelly63 citations
- Higher total energy costs strain the elderly, especially low-income, across 31 developed countries ↗Peipei Tian, Kuishuang Feng, Laixiang Sun et al.62 citations
- Tuning porosity of macroporous hydrogels enables rapid rates of stress relaxation and promotes cell expansion and migration ↗Bryan A. Nerger, Kirti Kashyap, Brendan T. Deveney et al.62 citations
- De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity ↗Rubul Mout, Ross C. Bretherton, Justin A. Decarreau et al.61 citations
- Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization ↗Srikanth Ryali, Yuan Zhang, Carlo de los Angeles et al.61 citations
- Siglec-15/sialic acid axis as a central glyco-immune checkpoint in breast cancer bone metastasis ↗Yixian Wang, Zhan Xu, Kuan‐Lin Wu et al.61 citations
- Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen–targeted therapies ↗Samir Zaidi, Jooyoung Park, Joseph Minhow Chan et al.61 citations
- Enhanced charge-carrier dynamics and efficient solar-to-urea conversion on Si-based photocathodes ↗Xiaoran Zhang, Yanhong Lyu, Chen Chen et al.60 citations
- Enhanced effects of species richness on resistance and resilience of global tree growth to prolonged drought ↗Yun‐Hao Bai, Zhiyao Tang60 citations
- Hormonal basis of sex differences in anesthetic sensitivity ↗Andrzej Z. Wasilczuk, Cole Rinehart, Adeeti Aggarwal et al.60 citations
- Identification and characterization of a small-molecule metallophore involved in lanthanide metabolism ↗Alexa M. Zytnick, Sophie M. Gutenthaler, Allegra T. Aron et al.60 citations
- Increased perfluorooctanoic acid accumulation facilitates the migration and invasion of lung cancer cells via remodeling cell mechanics ↗Jie Mei, Jipeng Jiang, Li Zhao et al.60 citations
- Laser-driven noncontact bubble transfer printing via a hydrogel composite stamp ↗Chenglong Li, Hongyu Luo, Xinyi Lin et al.60 citations
- Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson’s disease ↗Shahzad S. Khan, Ebsy Jaimon, Yu‐En Lin et al.60 citations
- Surging compound drought–heatwaves underrated in global soils ↗Xingwang Fan, Yunlin Zhang, Kun� Shi et al.60 citations
- The potential importance of the built-environment microbiome and its impact on human health ↗Thomas C. G. Bosch, Mark Wigley, Beatriz Colomina et al.60 citations
- Bacterial outer membrane vesicle nanorobot ↗Songsong Tang, Daitian Tang, Houhong Zhou et al.59 citations
- In vivo whole-cortex marker of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youth ↗Shaoshi Zhang, Bart Larsen, Valerie J. Sydnor et al.59 citations
- Predicting protein conformational motions using energetic frustration analysis and AlphaFold2 ↗Xingyue Guan, Qian-Yuan Tang, Weitong Ren et al.59 citations
- Rapid shift in methane carbon isotopes suggests microbial emissions drove record high atmospheric methane growth in 2020–2022 ↗Sylvia Michel, Xin Lan, John Bharat Miller et al.59 citations
- Uncommon and nonpartisan: Antidemocratic attitudes in the American public ↗Derek Edward Holliday, Shanto Iyengar, Yphtach Lelkes et al.59 citations
- Beyond genomics in Patescibacteria: A trove of unexplored biology packed into ultrasmall bacteria ↗Pooja Srinivas, Snow Brook Peterson, Larry A. Gallagher et al.58 citations
- Data-driven inverse design of flexible pressure sensors ↗Zhiguang Liu, Minkun Cai, Shenda Hong et al.58 citations
- Promoting sustainable smallholder farming via multistakeholder collaboration ↗Zhichao An, Yi Yang, Xue Qin Yang et al.58 citations
- Widespread seawater intrusions beneath the grounded ice of Thwaites Glacier, West Antarctica ↗Eric J. Rignot, E. Ciracì, B. Scheuchl et al.58 citations
- Dynamic carriers for therapeutic RNA delivery ↗Simone Berger, Ulrich Lächelt, Ernst Wagner57 citations
- Equity and modeling in sustainability science: Examples and opportunities throughout the process ↗Amanda Giang, Morgan R. Edwards, Sarah Marie Fletcher et al.57 citations
- Fast quantum interference of a nanoparticle via optical potential control ↗Lukas Neumeier, Mario Arnolfo Ciampini, Oriol Romero‐Isart et al.57 citations
- Migration and sustainable development ↗William Neil Adger, Sonja Fransen, Ricardo Safra de Campos et al.57 citations
- Opportunities and challenges of plant proteins as functional ingredients for food production ↗Lara Etzbach, Susanne Gola, Fabian Küllmer et al.57 citations
- Photomolecular effect: Visible light interaction with air–water interface ↗Guangxin Lv, Yaodong Tu, James H. Zhang et al.57 citations
- Synthesis of evidence yields high social cost of carbon due to structural model variation and uncertainties ↗Frances C. Moore, Moritz A. Drupp, James Rising et al.57 citations
- Cu(II) complex that synergistically potentiates cytotoxicity and an antitumor immune response by targeting cellular redox homeostasis ↗Ke-Bin Huang, Feng-Yang Wang, Yuan Lu et al.56 citations
- Curvature-mediated rapid extravasation and penetration of nanoparticles against interstitial fluid pressure for improved drug delivery ↗Xiaohe Jiang, Sai Xu, Yunqiu Miao et al.56 citations
- Steering lithium and potassium storage mechanism in covalent organic frameworks by incorporating transition metal single atoms ↗Yingnan Cao, Qing Xu, Yi Sun et al.56 citations
- Adaptive evolution of carbapenem-resistant hypervirulent Klebsiella pneumoniae in the urinary tract of a single patient ↗Shikai Song, Shixin Yang, Ruicheng Zheng et al.55 citations
- Bioengineering a plant NLR immune receptor with a robust binding interface toward a conserved fungal pathogen effector ↗Rafał Zdrzałek, Yuxuan Xi, Thorsten Langner et al.55 citations
- Genomes, fossils, and the concurrent rise of modern birds and flowering plants in the Late Cretaceous ↗Shaoyuan Wu, Frank E. Rheindt, Jin Zhang et al.55 citations
- How working from home reshapes cities ↗Arjun Ramani, Joel Alcedo, Nicholas Bloom55 citations
- Intratumor injected gold molecular clusters for NIR-II imaging and cancer therapy ↗Ani Baghdasaryan, Haoran Liu, Fuqiang Ren et al.55 citations
- Structure of the flotillin complex in a native membrane environment ↗Ziao Fu, Roderick MacKinnon55 citations
- Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer ↗Shi-Yang Li, Jan A. Hammarlund, Gang Wu et al.55 citations
- A disinhibitory circuit mechanism explains a general principle of peak performance during mid-level arousal ↗Lola Beerendonk, Jorge F. Mejías, Stijn Adriaan Nuiten et al.54 citations
- A wirelessly programmable, skin-integrated thermo-haptic stimulator system for virtual reality ↗Jae-Hwan Kim, Jae-Hwan Kim, Abraham Vázquez‐Guardado et al.54 citations
- Bacterial lifestyle shapes pangenomes ↗Anna E. Dewar, Chunhui Hao, Laurence J. Belcher et al.54 citations
- Contribution of anthropogenic aerosols to persistent La Niña-like conditions in the early 21st century ↗Yen‐Ting Hwang, Shang‐Ping Xie, Po-Ju Chen et al.54 citations
- Fatty acid oxidation fuels natural killer cell responses against infection and cancer ↗Sam Sheppard, Katja Srpan, Wendy Lin et al.54 citations
- Gut bacteria of lepidopteran herbivores facilitate digestion of plant toxins ↗Nan Zhang, Zhaoyi Qian, Jintao He et al.54 citations
- Hidden hotspots of amphibian biodiversity in China ↗Wei Xu, Wei Xu, Yun‐He Wu et al.54 citations
- IL7 increases targeted lipid nanoparticle–mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation ↗Caitlin M. Tilsed, Barzan A. Sadiq, Tyler Ellis Papp et al.54 citations
- Liquid water in the Martian mid-crust ↗Vashan Wright, Matthias Morzfeld, Michael Manga54 citations
- NSUN5/TET2-directed chromatin-associated RNA modification of 5-methylcytosine to 5-hydroxymethylcytosine governs glioma immune evasion ↗Ruixin Wu, Chunming Sun, Xi Chen et al.54 citations
- SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor ↗Mohamad Wessam Alnouri, Kenneth Anthony Roquid, Rémy Bonnavion et al.54 citations
- Single-cell profiling of African swine fever virus disease in the pig spleen reveals viral and host dynamics ↗Zixiang Zhu, Ruoqing Mao, Baohong Liu et al.54 citations
- The genome-wide signature of short-term temporal selection ↗Michael F. Lynch, Wen Wei, Zhiqiang Ye et al.54 citations
- Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues ↗Yulia Eygeris, Mohit Gupta, Jeonghwan Kim et al.54 citations
- Zinc oxide nanoparticles cooperate with the phyllosphere to promote grain yield and nutritional quality of rice under heatwave stress ↗Shuqing Guo, Xiangang Hu, Zixuan Wang et al.54 citations
- Collective behavior from surprise minimization ↗Conor Heins, Beren Millidge, Lancelot Da Costa et al.53 citations
- Direct electrochemical evidence suggests that aqueous microdroplets spontaneously produce hydrogen peroxide ↗Lynn E. Krushinski, Jeffrey E. Dick53 citations
- HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence ↗Mengying Cui, Koji Yamano, Kenichi Yamamoto et al.53 citations
- Learning shapes the development of migratory behavior ↗Ellen O. Aikens, Elham Nourani, Wolfgang Fiedler et al.53 citations
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