Proceedings of the National Academy of Sciences 2014: all accepted papers
- Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death ↗Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al.594 citations
- Shifts in flowering phenology reshape a subalpine plant community ↗Paul J. CaraDonna, Amy Marie Iler, David W. Inouye593 citations
- The Holocene temperature conundrum ↗Zhengyu Liu, Jiang Zhu, Yair Rosenthal et al.593 citations
- An uncoupling channel within the c-subunit ring of the F 1 F O ATP synthase is the mitochondrial permeability transition pore ↗Kambiz N. Alavian, Gisela Beutner, Emma Lazrove et al.592 citations
- High carbon dioxide uptake by subtropical forest ecosystems in the East Asian monsoon region ↗Guirui Yu, Zhi Chen, Shilong L. Piao et al.591 citations
- Metabolic costs and evolutionary implications of human brain development ↗Christopher W. Kuzawa, Harry T. Chugani, Lawrence I. Grossman et al.583 citations
- Bloom of resident antibiotic-resistant bacteria in soil following manure fertilization ↗Nikolina Udiković‐Kolić, Fabienne Wichmann, Nichole A. Broderick et al.582 citations
- Patterned progression of bacterial populations in the premature infant gut ↗Patricio Salvatore La Rosa, Barbara B. Warner, Yanjiao Zhou et al.573 citations
- High-strength cellular ceramic composites with 3D microarchitecture ↗Jens Bauer, Stefan Hengsbach, I. Tesari et al.563 citations
- Sugar demand, not auxin, is the initial regulator of apical dominance ↗Michael G. Mason, John J. Ross, Benjamin A. Babst et al.563 citations
- Autism as a disorder of prediction ↗Pawan Sinha, Margaret Kjelgaard, Tapan Kumar Gandhi et al.560 citations
- Global dissemination of a multidrug resistant Escherichia coli clone ↗Nicola K. Petty, Nouri L. Ben Zakour, Mitchell J. Stanton-Cook et al.558 citations
- Probing nuclear pore complex architecture with proximity-dependent biotinylation ↗Dae In Kim, Birendra KC, Wenhong Zhu et al.556 citations
- Platelets guide the formation of early metastatic niches ↗Myriam Labelle, Shahinoor Begum, Richard O. Hynes552 citations
- Endemism and functional convergence across the North American soil mycobiome ↗Jennifer M. Bhatnagar, Thomas D. Bruns, John William Taylor et al.551 citations
- Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle ↗Xuesong He, Jeffrey S. McLean, Anna Edlund et al.548 citations
- Navigability of interconnected networks under random failures ↗Manlio De Domenico, Albert Solé‐Ribalta, Sergio Gómez et al.548 citations
- A 3,500-year tree-ring record of annual precipitation on the northeastern Tibetan Plateau ↗Bao Shan Yang, Chun Qin, Jianglin Wang et al.546 citations
- Wireless power transfer to deep-tissue microimplants ↗John S. Ho, Alexander J. Yeh, Evgenios A. Neofytou et al.538 citations
- A taxonomy of prospection: Introducing an organizational framework for future-oriented cognition ↗Karl K. Szpunar, R. Nathan Spreng, Daniel L. Schacter536 citations
- Origin of myofibroblasts in the fibrotic liver in mice ↗Keiko Iwaisako, Chunyan Jiang, Mingjun Zhang et al.535 citations
- Terpene synthases are widely distributed in bacteria ↗Yuuki Yamada, Tomohisa Kuzuyama, Mamoru Komatsu et al.535 citations
- Meal frequency and timing in health and disease ↗Mark P. Mattson, David Blair Allison, Luigi Fontana et al.531 citations
- RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection ↗Wenhui Hu, Rafal Kaminski, Fan Yang et al.527 citations
- Effect of sleep deprivation on the human metabolome ↗Sarah K. Davies, Joo Ern Ang, Victoria Louise Revell et al.524 citations
- OsNAP connects abscisic acid and leaf senescence by fine-tuning abscisic acid biosynthesis and directly targeting senescence-associated genes in rice ↗Chengzhen Liang, Yiqin Wang, Yana Zhu et al.522 citations
- Global patterns of marine mammal, seabird, and sea turtle bycatch reveal taxa-specific and cumulative megafauna hotspots ↗Rebecca L. Lewison, Larry B. Crowder, Bryan P. Wallace et al.518 citations
- SPX1 is a phosphate-dependent inhibitor of PHOSPHATE STARVATION RESPONSE 1 in Arabidopsis ↗María Isabel Puga, Isabel Mateos, Charukesi Rajulu et al.512 citations
- Toward a theory of resilience for international development applications ↗Christopher B. Barrett, Mark A. Constas511 citations
- Thirty-thousand-year-old distant relative of giant icosahedral DNA viruses with a pandoravirus morphology ↗Matthieu Legendre, Julia Bartoli, Lyubov Shmakova et al.508 citations
- Conflict translates environmental and social risk into business costs ↗Daniel M. Franks, Rachel Davis, Anthony Bebbington et al.506 citations
- H-ferritin–nanocaged doxorubicin nanoparticles specifically target and kill tumors with a single-dose injection ↗Minmin Liang, Kelong Fan, Meng Zhou et al.506 citations
- Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides ↗Georg Meisl, Xiaoting Yang, Erik Hellstrand et al.505 citations
- Stromal response to Hedgehog signaling restrains pancreatic cancer progression ↗John J. Lee, Rushika M. Perera, Huaijun Wang et al.501 citations
- Genomic responses in mouse models greatly mimic human inflammatory diseases ↗Keizo Takao, Tsuyoshi Miyakawa500 citations
- A rice ABC transporter, OsABCC1, reduces arsenic accumulation in the grain ↗Won‐Yong Song, Tomohiro Yamaki, Naoki Yamaji et al.499 citations
- Urban adaptation can roll back warming of emerging megapolitan regions ↗Matei Georgescu, Philip E. Morefield, Britta Bierwagen et al.499 citations
- Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons ↗Jiang-Yan Yang, Evelyne Ruchti, Jean-Marie Petit et al.497 citations
- Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal ↗Pontus Skoglund, Bernd H. Northoff, M.V. Shunkov et al.497 citations
- Gaining trust as well as respect in communicating to motivated audiences about science topics ↗Susan T. Fiske, Cydney H. Dupree496 citations
- Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis ↗Ting Wang, Daniele M. Gilkes, Naoharu Takano et al.493 citations
- Investors prefer entrepreneurial ventures pitched by attractive men ↗Alison Wood Brooks, Laura Huang, Sarah Wood Kearney et al.493 citations
- Cell separation using tilted-angle standing surface acoustic waves ↗Xiaoyun Ding, Zhangli Peng, Sz‐Chin Steven Lin et al.490 citations
- Improving fatty acids production by engineering dynamic pathway regulation and metabolic control ↗Peng Xu, Lingyun Li, Fuming Zhang et al.487 citations
- Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates ↗Yizhou Dong, Kevin T. Love, J. Robert Dorkin et al.487 citations
- TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading ↗Christopher J. O’Conor, Holly A. Leddy, Halei C. Benefield et al.487 citations
- Volta potential phase plate for in-focus phase contrast transmission electron microscopy ↗Radostin Danev, Bart Buijsse, Maryam Khoshouei et al.487 citations
- Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression ↗Eric William Rogier, Aubrey L. Frantz, Maria E. C. Bruno et al.485 citations
- Influence of vapor wall loss in laboratory chambers on yields of secondary organic aerosol ↗Xuan Zhang, Christopher D. Cappa, Shantanu H. Jathar et al.484 citations
- Embers of society: Firelight talk among the Ju/’hoansi Bushmen ↗Polly Wiessner483 citations
- Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism ↗João Fadista, Petter J Vikman, Emilia Ottosson-Laakso et al.483 citations
- China’s international trade and air pollution in the United States ↗Jintai Lin, Da Pan, Steven J. Davis et al.481 citations
- Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO 2 fixation ↗Martin Könneke, Daniel M. Schubert, Philip C. Brown et al.480 citations
- Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma ↗Jennifer A. Perry, Adam Kieżun, Peter Tonzi et al.478 citations
- Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy ↗Jiujiu Yu, Hajime Nagasu, Tomohiko Murakami et al.477 citations
- α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation ↗Jacqueline Burré, Manu Sharma, Thomas C. Südhof477 citations
- Percolation transition in dynamical traffic network with evolving critical bottlenecks ↗Daqing Li, Bowen Fu, Yunpeng Wang et al.475 citations
- Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A ↗Kazuya Yamanaka, Kirk A. Reynolds, Roland D. Kersten et al.474 citations
- Automated identification of stratifying signatures in cellular subpopulations ↗Robert V. Bruggner, Bernd Bodenmiller, David L. Dill et al.473 citations
- Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization ↗Tibor Csorba, Julia I. Qüesta, Qianwen Sun et al.470 citations
- Evolutionary tipping points in the capacity to adapt to environmental change ↗Carlos A. Botero, Franz J. Weissing, JONATHAN M. WRIGHT et al.470 citations
- Noble gases identify the mechanisms of fugitive gas contamination in drinking-water wells overlying the Marcellus and Barnett Shales ↗Thomas H. Darrah, Avner Vengosh, Robert B. Jackson et al.469 citations
- Derivation of naïve human embryonic stem cells ↗Carol B. Ware, Angelique M. Nelson, Brigham H. Mecham et al.468 citations
- Land, irrigation water, greenhouse gas, and reactive nitrogen burdens of meat, eggs, and dairy production in the United States ↗Gidon Eshel, Alon Shepon, Tamar Makov et al.464 citations
- RETRACTED: Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells ↗Debangshu Samanta, Daniele M. Gilkes, Pallavi Chaturvedi et al.460 citations
- Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage ↗Whasil Lee, Holly A. Leddy, Yong Chen et al.460 citations
- Perennial grasslands enhance biodiversity and multiple ecosystem services in bioenergy landscapes ↗Benjamin P. Werling, Timothy L. Dickson, Rufus Isaacs et al.459 citations
- Rice SPX1 and SPX2 inhibit phosphate starvation responses through interacting with PHR2 in a phosphate-dependent manner ↗Zhiye Wang, Wenyuan Ruan, Jing Shi et al.456 citations
- Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice ↗Andrew J. Murphy, Lynn E. Macdonald, Sean Gregory Stevens et al.455 citations
- Soft spots and their structural signature in a metallic glass ↗Jun Cai Ding, Sylvain Patinet, Michael L. Falk et al.455 citations
- Tracking heavy water (D 2 O) incorporation for identifying and sorting active microbial cells ↗David Berry, Esther Mader, Tae Kwon Lee et al.455 citations
- Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes ↗Mark D. Szczelkun, Maria S. Tikhomirova, Tomas Šinkūnas et al.453 citations
- Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy ↗Nathaniel Huebsch, Cathal J. Kearney, Xuanhe Zhao et al.453 citations
- Rapid generation of a mouse model for Middle East respiratory syndrome ↗Jincun Zhao, Kun Li, Christine Wohlford-Lenane et al.452 citations
- Sulforaphane treatment of autism spectrum disorder (ASD) ↗Kanwaljit Singh, Susan L. Connors, Eric A. Macklin et al.448 citations
- Antarctic sea ice control on ocean circulation in present and glacial climates ↗Raffaele Ferrari, Malte Friedrich Jansen, Jess F. Adkins et al.445 citations
- Three-dimensionally printed biological machines powered by skeletal muscle ↗Caroline Cvetkovic, Ritu Raman, Vincent Chan et al.443 citations
- A computational and neural model of momentary subjective well-being ↗Robb B. Rutledge, Nikolina Skandali, Peter Dayan et al.442 citations
- Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance ↗Roberto Maldonado, Robert A. LaMothe, Joseph D. Ferrari et al.440 citations
- Giant and switchable surface activity of liquid metal via surface oxidation ↗Mohammad Rashed Khan, Collin B. Eaker, Edmond F. Bowden et al.434 citations
- Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms ↗Leslie I. Grad, Justin J. Yerbury, Bradley J. Turner et al.431 citations
- Nonlinear permanent migration response to climatic variations but minimal response to disasters ↗Pratikshya Bohra-Mishra, Michael Oppenheimer, Solomon Hsiang430 citations
- Functional trait space and the latitudinal diversity gradient ↗Christine A. Lamanna, Benjamin Wong Blonder, Cyrille Violle et al.428 citations
- Convergent evolution and parallelism in plant domestication revealed by an expanding archaeological record ↗Dorian Q. Fuller, Tim P. Denham, Manuel Arroyo‐Kalin et al.427 citations
- Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA ↗Jonathan E. Zuckerman, Ismael Gritli, Anthony W. Tolcher et al.427 citations
- Illegal killing for ivory drives global decline in African elephants ↗George Wittemyer, Joseph M. Northrup, Julian Blanc et al.426 citations
- Carlactone is converted to carlactonoic acid by MAX1 in Arabidopsis and its methyl ester can directly interact with AtD14 in vitro ↗Satoko Abe, Aika Sado, Kai Tanaka et al.425 citations
- DNA methylation of BDNF as a biomarker of early-life adversity ↗Marija Kundaković, Kathryn M. Gudsnuk, Julie Beth Herbstman et al.425 citations
- Discovery of LPMO activity on hemicelluloses shows the importance of oxidative processes in plant cell wall degradation ↗Jane W. Agger, Trine Isaksen, Anikó Várnai et al.425 citations
- Elite male faculty in the life sciences employ fewer women ↗Jason M. Sheltzer, Joan C. Smith425 citations
- Genomics and host specialization of honey bee and bumble bee gut symbionts ↗Waldan K. Kwong, Philipp Engel, Hauke Koch et al.424 citations
- Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals ↗Yanchang Wei, Cairong Yang, Yanping Wei et al.423 citations
- Deepwater Horizon crude oil impacts the developing hearts of large predatory pelagic fish ↗John P. Incardona, Luke D. Gardner, Tiffany L. Linbo et al.422 citations
- Gyrification from constrained cortical expansion ↗T. Tallinen, Jun Young Chung, John Simeon Biggins et al.422 citations
- Fluid shear stress threshold regulates angiogenic sprouting ↗Peter A. Galie, Duc-Huy T. Nguyen, Colin Kiwon Choi et al.421 citations
- Evolutionary origin of insect– Wolbachia nutritional mutualism ↗Naruo Nikoh, Takahiro Hosokawa, Minoru Moriyama et al.420 citations
- Precise estimates of mutation rate and spectrum in yeast ↗Yuan O. Zhu, Mark L. Siegal, David W. Hall et al.420 citations
- Comparison of the transcriptional landscapes between human and mouse tissues ↗Shin Lin, Yiing Lin, Joseph R. Nery et al.417 citations
- Visual account of protein investment in cellular functions ↗Wolfram Liebermeister, Εlad Noor, Avi I. Flamholz et al.416 citations
- Plant roots use a patterning mechanism to position lateral root branches toward available water ↗Yun Bao, Pooja Aggarwal, Neil E. Robbins et al.415 citations
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