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Nature 2025: all accepted papers

4,398 papers · page 1 of 44 · the most cited first · ← Nature 2025

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  1. DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learningDaya Guo, Dejian Yang, Haowei Zhang et al.1,099 citations · our summary
  2. Accurate predictions on small data with a tabular foundation model ↗Noah Hollmann, Samuel Müller, Lennart Purucker et al.974 citations
  3. A generative model for inorganic materials design ↗Claudio Zeni, Robert Pinsler, Daniel Zügner et al.498 citations
  4. Global evolution of inflammatory bowel disease across epidemiologic stages ↗Lindsay Hracs, Joseph W. Windsor, Julia Gorospe et al.455 citations
  5. 10,000-h-stable intermittent alkaline seawater electrolysis ↗Qihao Sha, Shiyuan Wang, Li Yan et al.452 citations
  6. RETRACTED ARTICLE: Warming accelerates global drought severity ↗Solomon H. Gebrechorkos, Justin Sheffield, Sergio Martín Vicente-Serrano et al.378 citations
  7. Neuromorphic computing at scale ↗Dhireesha Kudithipudi, Catherine D. Schuman, Craig Michael Vineyard et al.357 citations
  8. Impacts of climate change on global agriculture accounting for adaptation ↗Andrew Hultgren, Tamma A. Carleton, Michael Delgado et al.354 citations
  9. Towards conversational diagnostic artificial intelligence ↗Tao Tu, Mike Schaekermann, Anil Palepu et al.344 citations
  10. One-quarter of freshwater fauna threatened with extinction ↗Catherine Overed-Sayer, Eresha Fernando, Randall R. Jiménez et al.326 citations
  11. Immune evasion through mitochondrial transfer in the tumour microenvironment ↗Hideki Ikeda, Katsushige Kawase, Tatsuya Nishi et al.323 citations
  12. Mass-spectrometry-based proteomics: from single cells to clinical applications ↗Tiannan Guo, Judith A. J. Steen, Matthias Mann320 citations
  13. RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer ↗Zachary M. Sethna, Pablo Guasp, Charlotte Reiche et al.319 citations
  14. Atomically accurate de novo design of antibodies with RFdiffusion ↗Nathaniel R. Bennett, Joseph L. Watson, Robert J. Ragotte et al.310 citations
  15. The distribution of subsurface microplastics in the ocean ↗Shiye Zhao, Karin Kvale, Lixin Zhu et al.307 citations
  16. Towards accurate differential diagnosis with large language models ↗Daniel McDuff, Mike Schaekermann, Tao Tu et al.293 citations
  17. The global human impact on biodiversity ↗François Keck, Tianna Peller, Roman Alther et al.288 citations
  18. Activation of lysosomal iron triggers ferroptosis in cancer ↗Tatiana Cañeque, Leeroy Baron, Sebastian Müller et al.262 citations
  19. A foundation model for the Earth system ↗Cristian Bodnar, Wessel P. Bruinsma, Ana Lučić et al.249 citations
  20. A vision–language foundation model for precision oncology ↗Jinxi Xiang, Xiyue Wang, Xiaoming Zhang et al.249 citations
  21. Metal–support frontier orbital interactions in single-atom catalysis ↗Xianxian Shi, Zhilin Wen, Qingqing Gu et al.241 citations
  22. A natural experiment on the effect of herpes zoster vaccination on dementia ↗Markus Eyting, Min Xie, Felix Michalik et al.238 citations
  23. One-shot design of functional protein binders with BindCraft ↗Martin Pačesa, Lennart Nickel, Christian Schellhaas et al.236 citations
  24. A manufacturable platform for photonic quantum computing ↗PsiQuantum team, Koen Alexander, Avishai Benyamini et al.231 citations
  25. All-solid-state Li–S batteries with fast solid–solid sulfur reaction ↗Huimin Song, Konrad Münch, Xu Liu et al.229 citations
  26. Genomics yields biological and phenotypic insights into bipolar disorder ↗Kevin Sean O’Connell, Maria Koromina, Tracey van der Veen et al.212 citations
  27. Tailoring polymer electrolyte solvation for 600 Wh kg−1 lithium batteries ↗Xueyan Huang, Chen‐Zi Zhao, Wei-Jin Kong et al.210 citations
  28. Mapping the chemical complexity of plastics ↗Laura Monclús, Hans Peter H. Arp, Ksenia J. Groh et al.209 citations
  29. A neoantigen vaccine generates antitumour immunity in renal cell carcinoma ↗David A. Braun, Giorgia Moranzoni, Vipheaviny A. Chea et al.207 citations
  30. Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease ↗Nobukatsu Sawamoto, Daisuke Doi, Etsuro Nakanishi et al.202 citations
  31. All-perovskite tandem solar cells with dipolar passivation ↗Renxing Lin, Han Gao, Jing Lou et al.200 citations
  32. An integrated large-scale photonic accelerator with ultralow latency ↗Shiyue Hua, Erwan Divita, Shanshan Yu et al.199 citations
  33. Manipulation of the altermagnetic order in CrSb via crystal symmetry ↗Zhiyuan Zhou, Xingkai Cheng, Mengli Hu et al.199 citations
  34. Nanoplastic concentrations across the North Atlantic ↗Sophie ten Hietbrink, Dušan Materić, Rupert Holzinger et al.198 citations
  35. Community estimate of global glacier mass changes from 2000 to 2023 ↗The GlaMBIE Team, Michael Zemp, Livia Jakob et al.192 citations
  36. Distributed quantum computing across an optical network link ↗D. Main, P. Drmota, D. P. Nadlinger et al.192 citations
  37. Functional connectomics spanning multiple areas of mouse visual cortex ↗J. Alexander Bae, Mahaly Baptiste, Maya R. Baptiste et al.190 citations
  38. Acidic oxygen reduction by single-atom Fe catalysts on curved supports ↗Yasong Zhao, Jiawei Wan, Chongyi Ling et al.187 citations
  39. A brain-wide map of neural activity during complex behaviour ↗Leenoy Meshulam, Dora E. Angelaki, Julius Benson et al.179 citations
  40. Scaling and networking a modular photonic quantum computer ↗H. Aghaee Rad, T. Ainsworth, Rafael N. Alexander et al.178 citations
  41. The growing memristor industry ↗Mario Lanza, Sebastian Matias Pazos, Fernando Leonel Aguirre et al.177 citations
  42. Water structure and electric fields at the interface of oil droplets ↗Lixue Shi, R. Allen LaCour, Naixin Qian et al.177 citations
  43. Modular chiral origami metamaterials ↗Tuo Zhao, Xiangxin Dang, Konstantinos Manos et al.173 citations
  44. Machine-learning design of ductile FeNiCoAlTa alloys with high strength ↗Yasir Sohail, Chongle Zhang, Dezhen Xue et al.172 citations
  45. Wireless transmission of internal hazard signals in Li-ion batteries ↗Jinbao Fan, Chenchen Liu, Na Li et al.172 citations
  46. Geographic and age variations in mutational processes in colorectal cancer ↗Marcos Díaz‐Gay, Wellington dos Santos, Sarah Moody et al.170 citations
  47. Mastering diverse control tasks through world models ↗Danijar Hafner, Jurgis Pašukonis, Jimmy Lei Ba et al.170 citations
  48. Superconductivity in 5.0° twisted bilayer WSe2 ↗Yinjie Guo, Jordan Pack, Joshua Swann et al.170 citations
  49. Artificial intelligence for modelling infectious disease epidemics ↗Moritz U. G. Kraemer, Joseph L.-H. Tsui, Serina Y. Chang et al.169 citations
  50. Molecular and cellular dynamics of the developing human neocortex ↗Li Wang, Cheng Wang, Juan Moriano et al.167 citations
  51. Universal photonic artificial intelligence acceleration ↗Sufi R. Ahmed, Reza Baghdadi, Mikhail Bernadskiy et al.165 citations
  52. Large recoverable elastic energy in chiral metamaterials via twist buckling ↗Xin Fang, Dianlong Yu, Jihong Wen et al.164 citations
  53. De novo designed proteins neutralize lethal snake venom toxins ↗Susana Vázquez Torres, Melisa Bénard-Valle, Stephen P. Mackessy et al.163 citations
  54. GABAergic neuron-to-glioma synapses in diffuse midline gliomas ↗Tara Barron, Belgin Yalçın, Minhui Su et al.161 citations
  55. Data-driven de novo design of super-adhesive hydrogels ↗Hongguang Liao, Sheng Hu, Yang Hu et al.160 citations
  56. Interferometric single-shot parity measurement in InAs–Al hybrid devices ↗Microsoft Azure Quantum, Morteza Aghaee, Alejandro Alcaraz Ramirez et al.156 citations
  57. Li2ZrF6-based electrolytes for durable lithium metal batteries ↗Qingshuai Xu, Tan Li, Zhijin Ju et al.156 citations
  58. Nerve-to-cancer transfer of mitochondria during cancer metastasis ↗Gregory Hoover, Shila Gilbert, Olivia Curley et al.156 citations
  59. Phase I trial of hES cell-derived dopaminergic neurons for Parkinson’s disease ↗Viviane S. Tabar, Harini Sarva, Andrés M. Lozano et al.153 citations
  60. Engineered heart muscle allografts for heart repair in primates and humans ↗Ahmad Fawad Jebran, Tim Seidler, Malte Tiburcy et al.151 citations
  61. Microsatellite-based real-time quantum key distribution ↗Yang Li, Wen-Qi Cai, Ji-Gang Ren et al.151 citations
  62. The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies ↗Kyle Swanson, Wesley C. H. Wu, Nash L. Bulaong et al.150 citations
  63. Complete sequencing of ape genomes ↗DongAhn Yoo, Arang Rhie, Prajna Hebbar et al.149 citations
  64. Global meta-analysis shows action is needed to halt genetic diversity loss ↗Robyn E. Shaw, Katherine A. Farquharson, Michael W. Bruford et al.149 citations
  65. Programs, origins and immunomodulatory functions of myeloid cells in glioma ↗Tyler E. Miller, Chadi A. El Farran, Charles Couturier et al.145 citations
  66. Global emergence of unprecedented lifetime exposure to climate extremes ↗Luke Grant, Inne Vanderkelen, Lukas Gudmundsson et al.144 citations
  67. Mapping cells through time and space with moscot ↗Dominik Klein, Giovanni Palla, Marius Lange et al.143 citations
  68. Illuminating the multidimensional contributions of small-scale fisheries ↗Xavier Basurto, Nicolás L. Gutiérrez, Nicole Franz et al.142 citations
  69. Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease ↗Sophia M. Shi, Ryan J. Suh, D. Judy Shon et al.141 citations
  70. Massively parallel characterization of transcriptional regulatory elements ↗Vikram Agarwal, Fumitaka Inoue, Max Schubach et al.141 citations
  71. Observation of an ultra-high-energy cosmic neutrino with KM3NeT ↗S. Aiello, A. Albert, A.R Alhebsi et al.140 citations
  72. Characterization of single neurons reprogrammed by pancreatic cancer ↗Vera Thiel, Simon Renders, Jasper Panten et al.139 citations
  73. Encapsulated Co–Ni alloy boosts high-temperature CO2 electroreduction ↗Wenchao Ma, Jordi Morales‐Vidal, Jiaming Tian et al.139 citations
  74. Granzyme K activates the entire complement cascade ↗C. Donado, Erin Theisen, Fan Zhang et al.138 citations
  75. Toughened self-assembled monolayers for durable perovskite solar cells ↗Wenlin Jiang, Geping Qu, Xiaofeng Huang et al.138 citations
  76. Whole-genome sequencing of 490,640 UK Biobank participants ↗Manuscript Writing Group, Keren Carss, Bjarni V. Halldórsson et al.137 citations
  77. Perovskite heteroepitaxy for high-efficiency and stable pure-red LEDs ↗Keyu Wei, Tong Zhou, Yuanzhi Jiang et al.136 citations
  78. Shielding Pt/γ-Mo2N by inert nano-overlays enables stable H2 production ↗Zirui Gao, Aowen Li, Xingwu Liu et al.134 citations
  79. Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice ↗Kelly Jin, Zizhen Yao, Cindy T. J. van Velthoven et al.130 citations
  80. Complex genetic variation in nearly complete human genomes ↗Glennis A. Logsdon, Peter Ebert, Peter A. Audano et al.130 citations
  81. Human assembloid model of the ascending neural sensory pathway ↗Ji‐il Kim, Kent Imaizumi, Ovidiu F. Jurjuţ et al.130 citations
  82. Signatures of chiral superconductivity in rhombohedral graphene ↗Tonghang Han, Zhengguang Lu, Zach Hadjri et al.130 citations
  83. Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity ↗Jie Yang, Yumi Yamashita-Kanemaru, Benjamin I. Morris et al.128 citations
  84. IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer ↗Masataka Amisaki, Abderezak Zebboudj, Hiroshi Yano et al.127 citations
  85. Addressing the safety of next-generation batteries ↗Chuanbo Yang, Avtar Singh, Xiaofei Pu et al.126 citations
  86. Aqueous-based recycling of perovskite photovoltaics ↗Xun Xiao, Niansheng Xu, Xueyu Tian et al.126 citations
  87. Integrated biotechnological and AI innovations for crop improvement ↗Guotian Li, Linna An, Wanneng Yang et al.126 citations
  88. SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade ↗Adam Grippin, Christiano Marconi, Sage A. Copling et al.126 citations
  89. Spatially resolved mapping of cells associated with human complex traits ↗Liyang Song, Wenhao Chen, Junren Hou et al.125 citations
  90. A foundation model of transcription across human cell types ↗Xi Fu, Shentong Mo, Alejandro Buendia et al.124 citations
  91. Global engineering effects of soil invertebrates on ecosystem functions ↗Donghao Wu, Enzai Du, Nico Eisenhauer et al.123 citations

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